A new method on quantitative profiling of signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains was reported by Dierck et.al and published on Nature methods (2006,3:737-744). The new proteomic technique, termed OTM, is able to quantify tyrosine phosphorylation states with high sensitivity and specificity.

Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains. Dierck […]

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There are some interesting articles from Science’s e-market online on bechtop advances in proteomics and genomics study. More articles can be found from here.

Advances In : Proteomics Analysis and Automation
Isolating, purifying, and characterizing proteins involve an increasing range of technologies, complemented by sophisticated software tools.

Advances In : Cancer Research Tracking and Attacking
New mechanisms to […]