ChIP-on-chip is a genome-wide location analysis to identify protein-binding site, including promoters, enhancers, and other regulatory elements. Here is a nice ChIP-on-chip technique illustration from Keith Ching at UCSD.

Following is a protocol from nature for genome-wide transcriptional binding site analysis using ChIP-on-chip. The entire method takes 10 days to complete.

ChIP-on-chip protocol for genome-wide analysis of […]

Dr.Andrew Z.Fire from Stanford University and Dr. Craig C.Mello from University of Massachusetts Medical School shares 2006 Nobel prize in Physiology or Medicine for their achievement of “discovery of RNA interference - gene silencing by double-stranded RNA” announced on October 2, 2006.

Ongoing research programs are listed in their lab homepage:

Fire lab research program

Mello lab […]

Welcome to Life Science Online Collaboration wiki site, a meeting place to work on common interests. Anyone can contribute using any web browser. Life Science Online Collaboration wiki site encourages contribution and editing of pages, questions, answers, comments and updates.

Most of the articles have list of reviews that can be accessed freely.

Biotech […]

Here is the collection of apoptosis pathway illustrations. Some of them are available in poster when requested. Most of pathway illustrations give general overview of the apoptosis pathways.

Apoptosis Pathway: A General Overview
Apoptosis pathway
Biocarta apoptosis pathways (recommended, with legend)
Upstate apoptosis pathway
Apoptosis Pathway: A General Overview
APOPTOSIS PATHWAYS AND DRUG TARGETS POSTER (recommended, Nature review)
Apoptosis Induced […]

There are some interesting articles from Science’s e-market online on bechtop advances in proteomics and genomics study. More articles can be found from here.

Advances In : Proteomics Analysis and Automation
Isolating, purifying, and characterizing proteins involve an increasing range of technologies, complemented by sophisticated software tools.

Advances In : Cancer Research Tracking and Attacking
New mechanisms to […]

RNA interference was ranked one of the ten emerging technologies that will change your world.

MIT Technology Review’s editors chose RNAi as one of the ten emerging technologies in their feb., 2004 article. Full article.

Universal Translation
Synthetic Biology
Nanowires
Bayesian Machine Learning
T-Rays
Distributed Storage
RNA Interference
Power Grid Control
Microfluidic Optical Fibers
Personal Genomics

This is a selection of recently published Reviews, Perspectives and Highlights on RNA interference (RNAi), one of the hottest new topics in bioscience. >> Nature review web focus on RNA interference

In this short review authors summarized use of human house keeping gene in gene expression study.

Human housekeeping genes are compact.
Eisenberg E, Levanon EY
Trends Genet. 2003 Jul ; 19(7): 362-5

This web page lists all popular house keeping genes based on the review given above and a paper by Su et al. It’s a good reference […]