Multiplex PCR quantification of cellular signaling networks
Thursday, March 8th, 2007 by biowww netA new method on quantitative profiling of signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains was reported by Dierck et.al and published on Nature methods (2006,3:737-744). The new proteomic technique, termed OTM, is able to quantify tyrosine phosphorylation states with high sensitivity and specificity.
Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains. Dierck […]
